Query: NC_010939:321492 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete Lineage: Actinobacillus pleuropneumoniae; Actinobacillus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria General Information: Actinobacillus pleuropneumoniae serovar 7 str. AP76 is a clinical isolated from a pig lung. This organism is an obligate parasite of pigs. The bacterium colonizes and invades the porcine lower respiratory tract and can survive phagocytosis by macrophages, eventually resulting in the death of the macrophage cell. Three RTS toxins, which result in cell damage, are produced by this organism.
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General Information: This strain can suppress the diseases caused by Rhizoctonia solani and Pythium ultimum which affect cotton plants. The production of a number of antibiotics (pyrrolnitrin, pyoluteorin, and 2,4-diacetylphloroglucinol) as well as the production of siderophores (which may affect the ability of competing organisms to obtain environmental iron) by this strain can inhibit phytopathogen growth such as the above-mentioned fungi. The genome of this organism contains a number of genes, estimated at 5.7 % of the chromosome, that encode proteins that are involved in secondary metabolism. A large number of repeat elements (REP) are also found in the genome in greater numbers than in related Pseudomonas spp.