Query: NC_010939:1809446 Actinobacillus pleuropneumoniae serovar 7 str. AP76, complete
Lineage: Actinobacillus pleuropneumoniae; Actinobacillus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria
General Information: Actinobacillus pleuropneumoniae serovar 7 str. AP76 is a clinical isolated from a pig lung. This organism is an obligate parasite of pigs. The bacterium colonizes and invades the porcine lower respiratory tract and can survive phagocytosis by macrophages, eventually resulting in the death of the macrophage cell. Three RTS toxins, which result in cell damage, are produced by this organism.
Subject: NC_011852:1482343 Haemophilus parasuis SH0165, complete genome
Lineage: Haemophilus parasuis; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria
General Information: This organism is the causative agent of Glasser's disease in swine but is usually found as a commensal organism in the upper respiratory tract. Glasser's disease is responsible for significant losses in swine husbandry. The disease was first noted in 1910 by Glasser and the organism requires factor V (NAD - nicotinamide adenine dinucleotide) growth factor, like H. suis, but not factor X (iron porphyrin) which H. suis requires. Pathogenicity and virulence are often strain specific. Symptoms include fibrinous polyserositis (fibrous inflammation of serous membranes, polyarthritis (inflammation of multiple joints) and meningitis (inflammation of meninges)and pneumonia.