General Information: Candidatus Amoebophilus asiaticus 5a2 is an obligate endosymbiont found in Acanthamoeba sp. TUMSJ-321. This organism is a member of the highly diverse bacterial phylum Bacteroidetes which includes the endosymbiont lineages represented by the sister taxa Candidatus A. asiaticus and Candidatus Cardinium hertigii, a symbiont of arthropods.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.