Query: NC_010805:1576735 Burkholderia multivorans ATCC 17616 chromosome 2, complete Lineage: Burkholderia multivorans; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Isolated from soil enriched with anthranilate at 41C, Berkeley, CA, USA. This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.
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General Information: Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.