Pre_GI: SWBIT SVG BLASTP

Query: NC_010804:2206000 Burkholderia multivorans ATCC 17616 chromosome 1, complete

Lineage: Burkholderia multivorans; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Isolated from soil enriched with anthranilate at 41C, Berkeley, CA, USA. This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.

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Subject: NC_007951:1928906 Burkholderia xenovorans LB400 chromosome 1, complete sequence

Lineage: Burkholderia xenovorans; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Originally identified as Pseudomonas sp. LB400 that was found in contaminated soil in upstate New York, USA, this organism is now classified in the genus Burkholderia. Polychlorinated biphenyl-degrading bacterium. Member of the genus Burkholderia are versatile organisms that occupy a surprisingly wide range of ecological niches. These bacteria are exploited for biocontrol, bioremediation, and plant growth promotion purposes. Burkholderia xenovorans has been found on fungi, animals, and from human clinical isolates such as from cystic fibrosis (CF) patients. It may be tightly associated with white-rot fungus, as the degadation of lignin by the fungus results in aromatic compounds the bacterium can then degrade. This organism is exceptionally capable of degradation of polychlorinated biphenyls (PCBs), which are environmental pollutants, and thus it may play a role in bioremediation of polluted and toxic sites and is studied as a model bioremediator. PCBs can be utilized as the sole carbon and energy source by this organism. The pathways for degradation of PCBs have been extensively characterized at both the genetic and the molecular level and have become a model system for the bacterial breakdown of these very persistent environmental contaminants.