Pre_GI: SWBIT SVG BLASTP

Query: NC_010794:885500 Methylacidiphilum infernorum V4, complete genome

Lineage: Methylacidiphilum infernorum; Methylacidiphilum; Methylacidiphilaceae; Methylacidiphilales; Verrucomicrobia; Bacteria

General Information: Methylacidiphilum infernorum V4 was first discovered in Hell's Gate geothermal area in New Zealand. It is extremely acidophilic and is able to utilize methane as sole carbon source.

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Subject: NC_008343:2589680 Granulibacter bethesdensis CGDNIH1, complete genome

Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria

General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.