Pre_GI: SWBIT SVG BLASTP

Query: NC_010730:952574 Sulfurihydrogenibium sp. YO3AOP1, complete genome

Lineage: Sulfurihydrogenibium; Sulfurihydrogenibium; Hydrogenothermaceae; Aquificales; Aquificae; Bacteria

General Information: Carbon fixation. Unable to oxidize hydrogen although hydrogen oxidation was thought to be universal in this group. Isolated from near-neutral-pH terrestrial hot springs in Obsidian Pool in Yellowstone National Park, USA.

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BLASTP Alignment.txt

Subject: NC_018870:427357 Thermacetogenium phaeum DSM 12270 chromosome, complete genome

Lineage: Thermacetogenium phaeum; Thermacetogenium; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria

General Information: Nitrogen fixation. Thermophilic strictly anaerobic bacterium oxidizing acetate to CO2 in syntrophic association with a methanogenic partner. Capable of growing with various substrates such as alcohols and methylated nitrogen compounds, and to reduce sulfate in the presence of acetate. Isolated from sludge of an anaerobic digester run at 58 degrees C. Thermacetogenium phaeum is a strictly anaerobic, homoacetogenic bacterium. It is exceptional because it can use the homoacetogenic Wood-Ljungdahl (CO- dehydrogenase) pathway both for acetate formation and acetate oxidation. Acetate oxidation is possible only in syntrophic cooperation with a methanogenic partner which maintains a low hydrogen and/or formate concentration in the coculture. With this, the bacterium operates close to the thermodynamic equilibrium of substrate conversion, similar to other syntrophically fermenting bacteria such as Syntrophomonas wolfei the genomes of which have been sequenced as well in the recent past.