Pre_GI: SWBIT SVG BLASTP

Query: NC_010729:265791 Porphyromonas gingivalis ATCC 33277, complete genome

Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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BLASTP Alignment.txt

Subject: NC_007604:2213659 Synechococcus elongatus PCC 7942, complete genome

Lineage: Synechococcus elongatus; Synechococcus; Synechococcaceae; Chroococcales; Cyanobacteria; Bacteria

General Information: This strain is a freshwater organism and is extensively studied due to its circadian clock which controls the expression of upwards of 800 genes during a 24 hour period. These unicellular cyanobacteria are also known as blue green algae and along with Prochlorococcus are responsible for a large part of the carbon fixation that occurs in marine environments. Synechococcus have a broader distribution in the ocean and are less abundant in oligotrophic (low nutrient) regions. These organism utilize photosystem I and II to capture light energy. They are highly adapted to marine environments and some strains have evolved unique motility systems in order to propel themselves towards areas that contain nitrogenous compounds. An obligate photoautotroph, it has been studied extensively by an international research community with respect to acquisition of organic carbon, transport and regulation of nitrogen compounds, adaptation to nutrient stresses, and reponse to light intensity.