Pre_GI: SWBIT SVG BLASTP

Query: NC_010729:1549744 Porphyromonas gingivalis ATCC 33277, complete genome

Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

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BLASTP Alignment.txt

Subject: NC_014909:619407 Candidatus Blochmannia vafer str. BVAF chromosome, complete genome

Lineage: Blochmannia vafer; Blochmannia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Candidatus Blochmannia is an obligate bacterial associate of Camponotus and related ant genera. Blochmannia vafer was isolated from Camponotus vafer workers and larvae collected from a single colony in the Coronado National Forest near Portal, Arizona, USA. Blochmannia is located within bacteriocytes, where the bacterial cells float freely in the host cytoplasm, and within oocytes of queens.