Pre_GI: SWBIT SVG BLASTP

Query: NC_010717:4851000 Xanthomonas oryzae pv. oryzae PXO99A, complete genome

Lineage: Xanthomonas oryzae; Xanthomonas; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria

General Information: This strain is a representative strain of race 6 isolated in the Philippines. This plant pathogen affects rice plants by causing leaf blight, a major problem in Asian countries where rice production occurs on an industrial scale. This organism enters the xylem and spreads throughout the vascular tissue of the plant, which results in wilting of the plant, or to leaf blight if the infection occurs later in development. This genus consists of plant-specific yellow-pigmented microbes, some of which are economically important phytopathogens that devastate crops such as citrus plants, rice, beans, grape, and cotton. These organisms are almost exclusively found associated with their plant hosts and are not found free in the soil. Xanthomonas oryzae contains two pathovars which cause enconomically significant diseases in rice. Xanthomonas oryzae pathovar oryzae causes bacterial leaf blight which is one of the most serious diseases of rice. This disease is common in temperate and tropical areas and can cause significant crop loss.

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BLASTP Alignment.txt

Subject: NC_012563:1 Clostridium botulinum A2 str. Kyoto, complete genome

Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain was isolated from a case of infant botulism in Kyoto, Japan in 1978. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.