Query: NC_010682:661272 Ralstonia pickettii 12J chromosome 1, complete sequence Lineage: Ralstonia pickettii; Ralstonia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Ralstonia pickettii 12J was isolated from copper-contaminated sediment from a lake in Michigan, USA. In addition to being highly resistant to copper, strain 12J is also resistant to zinc and cadmium. Ralstonia pickettii can be isolated from a wide range of environmental and clinical samples. This species is a nocosomial pathogen. It is associated with infections caused by contaminated solutions, such as distilled water and intravenous solutions. Ralstonia pickettii strains resistant to heavy metals have also been isolated from heavy metal contaminated environments.
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General Information: ETEC is the leading cause of traveler's diarrhea, characterized by a large volume of watery diarrhea. ETEC primarily colonizes the small intestine by way of the pili. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.