Query: NC_010673:479552 Borrelia hermsii DAH, complete genome Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.
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General Information: Soil bacterium that can cause opportunistic infections. Ochrobactrum anthropi is an opportunistic human pathogen usually causing infection in association with indwelling medical devices, such as catheters and drainage tubes. This organism and related species have also been isolated from soil, activated sludge, and plants. Ochrobactrum anthropi is a Gram-negative, anaerobic, motile bacterium. A common soil bacteria, it was originally considered as an opportunistic pathogen, causing infections in immunocompromised patients, patients with indwelling catheters or peritoneal dialysis but it is now emerging as a more and more important nosocomial pathogen. The first case of human infection was described in 1980. It has been isolated from blood, the urogenital tract, respiratory tract and eyes, and it can be part of the normal intestinal flora. It is resistant to many antibiotics, especially the beta-lactams.