Pre_GI: SWBIT SVG BLASTP

Query: NC_010634:3250810 Yersinia pseudotuberculosis PB1/+, complete genome

Lineage: Yersinia pseudotuberculosis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Environmental bacterium that causes gastrointestinal disease. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. This organism was first isolated in 1883 by Malassez and Vignal and is termed pseudotuberculosis since it causes lesions in the lung that are similar to those observed during tuberculosis infection. It is ubiquitous in the environment and is a food and waterborne pathogen that affects animals as well as humans by causing gastroenteritis like Yersinia enterocolitica.

Subject: NC_009792:642881 Citrobacter koseri ATCC BAA-895, complete genome

Lineage: Citrobacter koseri; Citrobacter; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Citrobacter koseri ATCC BAA-895 is a clinical isolate from a human infant. Causative agent of neonatal meningitis. Citrobacter koseri, previously known as Citrobacter diversus, Levinea diversus or Levinea malonatica resides in a wide range of environments, including soil, water and food products. It is an occasional inhabitant of human and animal intestines, but is mainly characterized as being a causative agent of neonatal meningitis with an extreme high rate of multiple brain abscess initiations and a concomitant high moratility rate. The bacteria are used in neonatal rat models to study the mechanism of blood-brain barrier penetration, host immune response evasion and its resistance to phagocytotic killing.