Query: NC_010611:679862 Acinetobacter baumannii ACICU, complete genome Lineage: Acinetobacter baumannii; Acinetobacter; Moraxellaceae; Pseudomonadales; Proteobacteria; Bacteria General Information: Acinetobacter baumannii strain ACICU (also called H34) was isolated from an outbreak in an intensive care unit in Rome, Italy. This bacterium is commonly isolated from the hospital environment and hospitalized patients. It is an aquatic organism, and is often cultured from liquid medical samples such as respiratory secretions, wounds, and urine. Acinetobacter also colonizes irrigating solutions and intravenous solutions. Although it has low virulence, it is capable of causing infection. Most isolates recovered from patients represent colonization rather than infection. When infections do occur, they usually occur in the blood, or in organs with a high fluid content, such as the lungs or urinary tract.Infections by this organism are becoming increasingly problematic due to the high number of resistance genes found in clinical isolates. Some strains are now resistant to all known antibiotics. Most of these genes appear to have been transferred horizontally from other organisms.
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General Information: This organism was discovered in 1819 by Bizio who named the organism after the Italian physicist Serrati. It was considered a nonpathogenic organism until late in the 20th century, although pathogenicity was noted as early as 1913. Serratia marcescens is an opportunistic human pathogen that is increasingly associated with life-threatening hospital-acquired infections. It is an environmental organism that has a broad host range, and is capable of infecting vertebrates and invertebrates, as well as plants. In humans, Serratia marcescens can cause meningitis (inflammation of the membrane surrounding the brain and spinal cord), endocarditis (inflammation of heart muscle) and pyelonephritis (inflammation of the kidneys). Many strains are resistant to multiple antibiotics. Environmental isolates are noted by production of the red pigment prodigiosin.