Query: NC_010571:4483500 Opitutus terrae PB90-1, complete genome Lineage: Opitutus terrae; Opitutus; Opitutaceae; Opitutales; Verrucomicrobia; Bacteria General Information: Opitutus terrae is a member of the Verrucomicrobia, a diverse phylum of organisms common in many terrestrial and aquatic habitats. This organism was isolated from rice paddy soil and has been detected in peat bog soil and other anoxic terrestrial environments.
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General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.