Query: NC_010554:2789722 Proteus mirabilis HI4320, complete genome
Lineage: Proteus mirabilis; Proteus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Proteus mirabilis is a tetracycline resistant human urinary tract isolate. This bacterium is part of the normal gut flora of a healthy individual, but is also an opportunistic pathogen. Flagellar movement allows this organism to travel through the urinary tract into the bladder and kidney where it may cause infection or stones. Cell death is caused by hemolysin, a pore-forming toxin which disrupts osmotic balance across the host cell membrane. This species is inherently resistant to nitrofuran and tetracycline, and some strains have recently become resistant to ampicillin and trimethoprin.
Subject: NC_006274:5267585 Bacillus cereus E33L, complete genome
Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: This strain (originally ZK, now E33L; Ethosha National Park, Namibia; isolate number 33; Large colony) was isolated from a swab of a dead zebra carcass in April, 1996. Soil microorganism that can cause food poisoning. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.