Pre_GI: SWBIT SVG BLASTP

Query: NC_010531:428000 Polynucleobacter necessarius STIR1, complete genome

Lineage: Polynucleobacter necessarius; Polynucleobacter; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: This strain is an obligate intracellular endosymbiont of the cilliate Euplotes aediculatus. This group of organisms is common in freshwater, comprising up to 60% of the bacteria in freshwater habitats. Polynucleobacter species are also known to be endosymbionts of ciliates. These strains live within the cytoplasm and are essential for their host organisms.

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Subject: NC_013316:1 Clostridium difficile R20291, complete genome

Lineage: Peptoclostridium difficile; Peptoclostridium; Peptostreptococcaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium difficile R20291 was isolated in Stoke Mandeville Hospital, UK in 2006 and is closely related to the North American hypervirulent BI strains. Clostridium difficile, a Gram-positive, spore-forming anaerobic bacterium, is the leading cause of infectious diarrhea among patients in hospitals worldwide, causing C. difficile infection (CDI). An important nosocomial pathogen, it is frequently associated with antibiotic treatment and causes diseases ranging from antibiotic-associated diarrhea to life-threatening pseudomembraneous colitis.