Query: NC_010531:428000 Polynucleobacter necessarius STIR1, complete genome Lineage: Polynucleobacter necessarius; Polynucleobacter; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria General Information: This strain is an obligate intracellular endosymbiont of the cilliate Euplotes aediculatus. This group of organisms is common in freshwater, comprising up to 60% of the bacteria in freshwater habitats. Polynucleobacter species are also known to be endosymbionts of ciliates. These strains live within the cytoplasm and are essential for their host organisms.
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General Information: This organism is the causative agent of Glasser's disease in swine but is usually found as a commensal organism in the upper respiratory tract. Glasser's disease is responsible for significant losses in swine husbandry. The disease was first noted in 1910 by Glasser and the organism requires factor V (NAD - nicotinamide adenine dinucleotide) growth factor, like H. suis, but not factor X (iron porphyrin) which H. suis requires. Pathogenicity and virulence are often strain specific. Symptoms include fibrinous polyserositis (fibrous inflammation of serous membranes, polyarthritis (inflammation of multiple joints) and meningitis (inflammation of meninges)and pneumonia.