Query: NC_010524:3445641 Leptothrix cholodnii SP-6, complete genome Lineage: Leptothrix cholodnii; Leptothrix; Comamonadaceae; Burkholderiales; Proteobacteria; Bacteria General Information: Leptothrix cholodnii SP-6 was isolated from water and flocculent from an artificial iron seep in Ithaca, NY, USA. Leptothrix cholodnii, like other Leptothrix species is an iron- and manganese-oxidizing, sheathed bacterium common in organic rich aquatic environments. Iron oxides and manganese oxides often coat the sheathes of these organisms.
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General Information: This species is associated with infections in cystic fibrosis patients. It is an important opportunistic pathogen, colonizing the lungs and associated with a decrease in long-term survival. A minority of patients with this infection may also develop "cepacia syndrome", which leads to an acute clinical decline which is frequently fatal. This species is a member of the Burkholderia cepacia complex, although it does not appear to spread from patient to patient as do the other members of the group.