Pre_GI: SWBIT SVG BLASTP

Query: NC_010513:542312 Xylella fastidiosa M12 chromosome, complete genome

Lineage: Xylella fastidiosa; Xylella; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria

General Information: Causal agent of citrus variegated chlorosis. This organism was first identified in 1993 as the causal agent of citrus variegated chlorosis, a disease that affects varieties of sweet oranges. This disease was first noticed in Brazil in 1987, and it greatly affects commercial orchards resulting in crop devastation worldwide. Other strains of this species cause a range of diseases in mulberry, pear, almond, elm, sycamore, oak, maple, pecan and coffee which collectively result in multimillion dollar devastation of economically important plants. The bacteria are transmitted from the gut of the insect vector (sharpshooter leafhopper) to the plant xylem (water conducting system) when the insect feeds. Xylella fastidiosa is similar to Xanthomonas campestris pv. campestris in that it produces a wide variety of pathogenic factors for colonization in a host-specific manner including a large number of fimbrial and afimbrial adhesins for attachment. It does not contain a type III secretion system, but possesses genes for a type II secretion system for export of exoenzymes that degrade the plant cell wall and allow the bacterium to colonize the plant xylem. The cell produces an exopolysaccharide that is similar to the xanthan gum produced by Xanthomonas campestris pv. campestris.

Subject: NC_002745:2152000 Staphylococcus aureus subsp. aureus N315, complete genome

Lineage: Staphylococcus aureus; Staphylococcus; Staphylococcaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain is a methicillin-resistant (MRSA) strain isolated in 1982 from a pharyngeal smear of a Japanese patient. Causes skin infections. Staphylcocci are generally found inhabiting the skin and mucous membranes of mammals and birds. Some members of this genus can be found as human commensals and these are generally believed to have the greatest pathogenic potential in opportunistic infections. This organism is a major cause of nosocomial (hospital-acquired) and community-acquired infections. S. aureus continues to be a major cause of mortality and is responsible for a variety of infections including, boils, furuncles, styes, impetigo and other superficial skin infections in humans. Also known to cause more serious infections particularly in the chronically ill or immunocompromised. The ability to cause invasive disease is associated with persistance in the nasal cavity of a host.