Query: NC_010424:214640 Candidatus Desulforudis audaxviator MP104C, complete genome Lineage: Desulforudis audaxviator; Desulforudis; Peptococcaceae; Clostridiales; Firmicutes; Bacteria General Information: Its genome indicates a motile, sporulating, sulfate-reducing, chemoautotrophic thermophile that can fix its own nitrogen and carbon by using machinery shared with archaea. Candidatus Desulforudis audaxviator is a gram positive sulfate reducing bacteria identified in fracture water from a borehole at a depth of 2.8 km in a South African gold mine. Water from these boreholes is very old (low-biodiversity fracture water), suggesting that these bacteria have been isolated from the Earth's surface for as much as several million years.
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General Information: This organism has been implicated in a range of hypersensitivity pneumonitides, including farmer's lung disease. Symptoms of the disease develop in susceptible individuals following the inhalation of spores from overheated materials such as moldy hay and bagasse, or from forced-air heating and humidification systems. Prolonged exposure to the antigens results in acute respiratory distress which may lead to irreversible lung damage. Saccharomonospora viridis DSM 43017 was isolated from Irish peat and was originally classified as Thermomonospora viridis.