Query: NC_010397:4150596 Mycobacterium abscessus chromosome Chromosome, complete sequence
Lineage: Mycobacterium abscessus; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Mycobacterium abscessus, formerly Mycobacterium chelonae subsp. abscessus, is a rapid-growing Mycobacterium sp., commonly isolated from soil and water. This organism causes a chronic lung infection, similar to tuberculosis, in patients with cystic fibrosis. Mycobacterium abscessus also causes wound and ear infections, and in immunosuppressed patients causes a generalized skin infection. This organism is very resistant to many commonly used antibiotics, which makes treatment difficult.
Subject: NC_002944:1285436 Mycobacterium avium subsp. paratuberculosis K-10, complete genome
Lineage: Mycobacterium avium; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a diary herd in Wisconsin, USA in the 1970's. Environmental organism which causes infections in birds and humans. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, Mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. Mycobacterium avium is ubiquitous in the environment, and can be found in stagnant waters and soils. This organism causes tuberculosis in birds and disseminated infections in immunocompromized humans (the elderly, children, and especially patients with AIDS). Infection results in a characteristic pulmonary disease which requires expensive drug therapy for successful treatment. Most prevalent colony morphotypes are smooth opaque, smooth transparent and rough, with the last two being the faster growers in vivo.