Query: NC_010338:4015928 Caulobacter sp. K31, complete genome Lineage: Caulobacter; Caulobacter; Caulobacteraceae; Caulobacterales; Proteobacteria; Bacteria General Information: Caulobacter strain K31 was isolated in an enrichment culture for chlorophenol-tolerant bacteria in groundwater from Karkola, Finland, which percolates through nutrient-poor silt and clay, and is cold (7-8oC), oxygen-deficient, iron-rich, and mildly acidic (pH 6-6.5).
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.