Query: NC_010336:996661 Francisella philomiragia subsp. philomiragia ATCC 25017, complete Lineage: Francisella philomiragia; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria General Information: Francisella philomiragia subsp. philomiragia ATCC 25017 was isolated from water in the Bear River Refuge in Utah, USA. Causes disease in humans and fish. Francisella philomiragia, formerly Yersinia philomiragia, has been isolated from water, muskrats, fish and humans. F. philomiragia is able to cause an often fatal bacteremia in people with chronic granulomatous disease. This supspecies can also cause pneumonia in near-drowning victims.
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General Information: This bacterium causes a contagious disease of cattle causing respiratory disease, mastitis, and arthritis. It is found worldwide and is inherently resistant to certain groups of antibiotics because it does not possess a cell wall. More recently, this species has become resistant to tetracycline, tilmicosin and spectinomycin which have been traditionally used in its control. The disease is spread between herds by the transfer of infected but seemingly healthy animals which shed viruses. It has also been introduced into healthy herds via frozen semen collected from an infected bull. The economic losses and negative impact on international trade from this disease have been considerable, and efforts are now underway to develop a vaccine.