Query: NC_010320:881351 Thermoanaerobacter sp. X514 chromosome, complete genome Lineage: Thermoanaerobacter; Thermoanaerobacter; Thermoanaerobacteraceae; Thermoanaerobacterales; Firmicutes; Bacteria General Information: This strain was isolated by anaerobic enrichment culture from a deep subsurface sample (2000 m below the surface) taken from a core hole at the Piceance Basin, Colorado, USA. It can use a variety of electron donors, including glucose, acetate, hydrogen and xylose while reducing iron, chromium and uranium at 60 degrees C.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.