Pre_GI: SWBIT SVG BLASTP

Query: NC_010263:278463 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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BLASTP Alignment.txt

Subject: NC_011988:1036618 Agrobacterium vitis S4 chromosome 2, complete genome

Lineage: Agrobacterium vitis; Agrobacterium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Agrobacterium vitis is the causative agent of crown gall disease in grapes. Agrobacterium are Gram-negative, motile, soil-dwelling plant pathogens with the species name given based on the disease phenotype associated with the bacteria. Disease causing Agrobacterium spp. possess a tumor-inducing (Ti) plasmid, which carries genes for the formation of opines. A segment of the Ti plasmid gets transferred to the plant cell and integrates into the host cell genome. The plant cell then starts synthesizing opines, which can be catabolized by Agrobacterium spp, but not by the plant cells.