Pre_GI: SWBIT SVG BLASTP

Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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BLASTP Alignment.txt

Subject: NC_013009:608515 Neorickettsia risticii str. Illinois, complete genome

Lineage: Neorickettsia risticii; Neorickettsia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Neorickettsia risticii str. Illinois was isolated from horse blood in Maryland, USA. Neorickettsia risticii, formerly Ehrlichia risticii, is an obligate intracellular bacterium related to the Rickettsia. It can be transmitted from flukes that infest snails, fish or aquatic insects to horses by ingestion. This organism causes Potomac horse fever, also knows as equine monocytic ehrlichiosis, an acute diarrheal disease.