Pre_GI: SWBIT SVG BLASTP

Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome

Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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BLASTP Alignment.txt

Subject: NC_009850:1862602 Arcobacter butzleri RM4018, complete genome

Lineage: Arcobacter butzleri; Arcobacter; Campylobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: Arcobacter butzleri RM4018 was isolated from a human patient with gastroenteritis. Causes gastroenteritis in humans. Arcobacter butzleri is a member of the family Campylobacteraceae, related to the human pathogenic Campylobacter spp. and the environmental Sulfurospirillum spp. A. butzleri is mainly found in livestock and water/marine environments and can cause gastroenteritis and bacteremia in humans.