Query: NC_010263:167450 Rickettsia rickettsii str. Iowa, complete genome Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: Causative agent for Rocky Mountain Spotted Fever. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.
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General Information: This strain was isolated from the Sargasso Sea at a depth of 90 m (34o 45.5'N; 66o 11.1'W). This strain belongs to the 'high light-adapted' ecotype, clade II, and has a low Chl b/a2 ratio. Marine cyanobacterium. This non-motile bacterium is a free-living marine organism that is one of the most abundant, as well as the smallest, on earth, and contributes heavily to carbon cycling in the marine environment. This cyanobacterium grows in areas of nitrogen and phosphorus limitation and is unique in that it utilizes divinyl chlorophyll a/b proteins as light-harvesting systems instead of phycobiliproteins. These pigments allow harvesting of light energy from blue wavelengths at low light intensity.