Query: NC_010184:3675424 Bacillus weihenstephanensis KBAB4, complete genome Lineage: Bacillus weihenstephanensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria General Information: Bacillus weihenstephanensis is a psychrotolerant member of the Bacillus species. This organism can grow at temperatures of 7 degrees C. Bacillus weihenstephanensis is a non-pathogenic, Gram-positive, typical facultative psychrophile generally found in soil.
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General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.