Query: NC_010163:63209 Acholeplasma laidlawii PG-8A chromosome, complete genome Lineage: Acholeplasma laidlawii; Acholeplasma; Acholeplasmataceae; Acholeplasmatales; Tenericutes; Bacteria General Information: Acholeplasma species are widely distributed in the nature and can be detected and isolated from different plant, avian, and mammalian sources. Acholeplasma laidlawii is found in soil, compost, wastewaters, cell cultures as well as in human tissues and in many animal species (birds, bovine, goat, equine, ovine, porcine, feline, rodent, primates). Acholeplasma laidlawii is capable of synthesizing glucose using a pyrophosphate-dependent 6-phosphofructokinase which has also been detected in other acholeplasmas (a good example of flexible metabolism). Additionally, Acholeplasma laidlawii and phytoplasmas are the only mollicutes known to use the universal genetic code, in which UGA is a stop codon.
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General Information: This strain was isolated from a culture of the dinoflagellate Pfiesteria piscicida CCMP1830 which has been implicated in many large scale algal blooms resulting in increased mortality in fish. The bacteria are attached to the surface of the dinoflagellate and in some ways allow the dinoflagellate to grow as those lacking the bacteria die off. The bacterium also chemotaxes towards the dinoflagellate product DMSP (dimethylsulfoniopropionate) and metabolizes it. DMSP is a major source of sulfur in marine ecosystems and plays a role in the sulfur biogeochemical cycle. The implication is a tight association between these important dinoflagellates and this marine bacterium.