Query: NC_010163:63209 Acholeplasma laidlawii PG-8A chromosome, complete genome Lineage: Acholeplasma laidlawii; Acholeplasma; Acholeplasmataceae; Acholeplasmatales; Tenericutes; Bacteria General Information: Acholeplasma species are widely distributed in the nature and can be detected and isolated from different plant, avian, and mammalian sources. Acholeplasma laidlawii is found in soil, compost, wastewaters, cell cultures as well as in human tissues and in many animal species (birds, bovine, goat, equine, ovine, porcine, feline, rodent, primates). Acholeplasma laidlawii is capable of synthesizing glucose using a pyrophosphate-dependent 6-phosphofructokinase which has also been detected in other acholeplasmas (a good example of flexible metabolism). Additionally, Acholeplasma laidlawii and phytoplasmas are the only mollicutes known to use the universal genetic code, in which UGA is a stop codon.
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General Information: This organism (Ureaplasma urealyticum biovar 1) is normally found as a commensal organism in the human genital tract. As an opportunistic pathogen, it can cause a sexually-transmitted disease and is recognized as causing non-chlamydial non-gonococcal urethritis. It can also cause obstetric complications in pregnant women, severe infections in infants, as well as meningitis. Like other Mollicutes, it is a wall-less bacterium and has undergone marked genome reduction. This organism appears to generate ATP through the hydrolysis of urea by the urease enzyme.