Query: NC_010162:573709 Sorangium cellulosum 'So ce 56', complete genome Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.
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General Information: Isolation: mud in British Guyana; Temp: Mesophile; Temp: 37 C; Habitat: Mud. Desulfovibrio are sulfate-reducing bacteria which reduce sulfate to sulfide found in soil, freshwater, saltwater and the intestinal tract of animals. These organisms typically grow anaerobically, although some can tolerate oxygen, and they utilize a wide variety of electron acceptors, including sulfate, sulfur, nitrate, and nitrite, as well as others. A number of toxic metals are reduced, including uranium (VI), chromium (VI) and iron (III), making these organisms of interest as bioremediators. These organisms are responsible for the production of poisonous hydrogen sulfide gas in marine sediments and in terrestrial environments such as drilling sites for petroleum products.