Pre_GI: SWBIT SVG BLASTP

Query: NC_010162:573709 Sorangium cellulosum 'So ce 56', complete genome

Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria

General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.

Subject: NC_005125:4117096 Gloeobacter violaceus PCC 7421, complete genome

Lineage: Gloeobacter violaceus; Gloeobacter; ; Gloeobacterales; Cyanobacteria; Bacteria

General Information: This organism was isolated from a calcereous (chalky) rock in Switzerland. Photosynthetic bacterium. This organism is an obligate photoautotroph that lacks thylakoid membranes and probably has its photosynthetic machinery in the cytoplasmic membrane with various components exposed to the periplasm whereas in other cyanobacteria the components are situated in the thylakoid membrane and are exposed to the cytoplasm. This unusual arrangement may be due to the lack of various fatty acids that are found in the thylakoid membrane in other cyanobacteria. It has been predicted that this organism was one of the earliest to diverge from the cyanobacterial line.