Pre_GI: SWBIT SVG BLASTP

Query: NC_010162:1222000 Sorangium cellulosum 'So ce 56', complete genome

Lineage: Sorangium cellulosum; Sorangium; Polyangiaceae; Myxococcales; Proteobacteria; Bacteria

General Information: Sorangium cellulosum 'So ce 56' produces a large number of bioactive compounds, such as, the antifungal soraphen and the anticancer agent epothilone. This organism, like other myxobacteria, undergoes a complex development and differentiation pathway. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100 000 cells. The motility system is not dependent on flagella like most bacteria, but instead relies on twitching pili: short extracellular appendages that may function analogously to oars in a rowboat. The myxobacteria have proved to be a rich source of novel natural products. Sorangium cellulosum produces a number of antibacterial, antifungal and cytotoxic substances which are being studies for therapeutic applications.

Subject: NC_008254:534590 Mesorhizobium sp. BNC1, complete genome

Lineage: Chelativorans; Chelativorans; Phyllobacteriaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This organism was isolated from a mixed-culture enriched from sewage using the chelating agent EDTA (binds divalent cations - ethylenediamine tetraacetic acid) as the sole carbon and nitrogen source. EDTA is often found at toxic waste sites where it is bound to metals and radionuclides, which affects bioremediation efforts. This bacterium is capable of EDTA degradation by itself.