Query: NC_010159:3448490 Yersinia pestis Angola, complete genome Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria General Information: This strain was isolated prior to 1985 and belongs to the antiqua biovar. It can ferment rhamnonse and melibiose which is a property usually associated with Yersinia pseudotuberculosis. Strain Angola belongs to a group of atypical Yersinia pestis strains with genotypic similarities that are intermediate between Y. pestis and Y. pseudotuberuclosis strains. Genotypic studies indicate that strain Angola is the oldest Y. pestis strain analyzed to date. It carries three plasmids that are similar to other Y. pestis plasmids but have aberrant sizes. The critical virulence factor, the V antigen, is different than that encoded by typical strains of Y. pestis and there is a deletion that affects the F1 operon. Strain Angola has been shown to be virulent by aerosol in mice.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This strain (HS; serotype O9) is a human commensal that was originally isolated from a laboratory scientist at Walter Reed Army Institute of Research in 1978 (Levine, 1978). Strain HS colonizes the human gastrointestinal tract in challenge experiments, but no overt signs of disease occur. Thus, this strain represents a genomic baseline for human gastrointestinal tract colonization. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.