Pre_GI: SWBIT SVG BLASTP

Query: NC_010120:2029880 Neisseria meningitidis 053442, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_007912:1231436 Saccharophagus degradans 2-40, complete genome

Lineage: Saccharophagus degradans; Saccharophagus; Alteromonadaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: This strain is a marine gamma-proteobacterium that was isolated from decaying Spartina alterniflora, a salt marsh cord grass, in the Chesapeake Bay, USA. Saccharophagus degradans 2-40 has been used to produce ethanol from plant material and may be useful for the production bioethanol. Bacterium able to degrade complex carbohydrates. Saccharophagus degradans is capable of degrading insoluble complex carbohydrates through the collective action of enzyme complexes found on its cell surfaces, utilizing the degradation products as a carbon source. This organism may be useful in bioremediation. The degradative enzymes this organism produces are typically exoenzymes that are collected and organized into large surface complexes termed cellulosomes.