Pre_GI: SWBIT SVG BLASTP

Query: NC_010103:1777000 Brucella canis ATCC 23365 chromosome I, complete sequence

Lineage: Brucella canis; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Etiologic agent of canine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This bacterium is the causative agent of canine brucellosis. The main sources of infection are vaginal fluids of infected females and urine in males. The most significant symptoms are late abortions in bitches, epididymitis in males and infertility in both sexes, as well as generalized lymphadenitis, discospondylitis and uveitis. Human contagion is not frequent, although it has been reported, and is easily treated. B. canis can be differentiated from the other species of the genus Brucella (except B. ovis) in that it forms rugose colonies.

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BLASTP Alignment.txt

Subject: NC_014760:299392 Mycoplasma bovis PG45 chromosome, complete genome

Lineage: Mycoplasma bovis; Mycoplasma; Mycoplasmataceae; Mycoplasmatales; Tenericutes; Bacteria

General Information: This bacterium causes a contagious disease of cattle causing respiratory disease, mastitis, and arthritis. It is found worldwide and is inherently resistant to certain groups of antibiotics because it does not possess a cell wall. More recently, this species has become resistant to tetracycline, tilmicosin and spectinomycin which have been traditionally used in its control. The disease is spread between herds by the transfer of infected but seemingly healthy animals which shed viruses. It has also been introduced into healthy herds via frozen semen collected from an infected bull. The economic losses and negative impact on international trade from this disease have been considerable, and efforts are now underway to develop a vaccine.