Query: NC_010080:445398 Lactobacillus helveticus DPC 4571, complete genome Lineage: Lactobacillus helveticus; Lactobacillus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria General Information: Lactic acid bacterium used in the manufacture of cheese. The homofermentative thermophilic lactic acid bacterium that is used in the manufacture of Swiss type and long-ripened Italian cheeses, such as Emmental, Grana, and Provolone cheeses.
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General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.