Query: NC_010003:1052997 Petrotoga mobilis SJ95, complete genome Lineage: Petrotoga mobilis; Petrotoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria General Information: Petrotoga mobilis SJ95 (DSM 10674) is an anaerobic thermophile, isolated from the production waters of a North Sea oil reservoir. This organism, a member of the Thermotogales, has the characteristic morphology of one or more cells contained in a sheath-like envelope which extends beyond the cell wall. Petroleum reservoirs are a unique subsurface environment characterized by high temperatures, moderate to high salt concentrations, and abundant organic matter.
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General Information: This strain was isolated in the USA from the soft tick Ornithodoros turicatae. Borrelia turicatae is the causative agent of tick-borne relapsing fever in the southwestern USA. Ticks become infected with Borrelia while feeding on an infected mammal, usually a rodent or squirrel. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the spirochete into a mammalian host through its infectious saliva. Relapsing fever is characterized by period of chills, fever, headache, and malaise, followed by an asymptomatic, followed by another episode of symptoms. The cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.