Query: NC_010001:4128034 Clostridium phytofermentans ISDg, complete genome Lineage: Lachnoclostridium phytofermentans; Lachnoclostridium; Lachnospiraceae; Clostridiales; Firmicutes; Bacteria General Information: Isolated from forest soil near the Quabbin Reservoir in Massachusetts, USA. This organism plays an important industrial and ecological role in the anaerobic fermentation of cellulose and produces economically significant levels of acetate and ethanol. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA.
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General Information: This pathogenic strain was isolated from an infected pig in Lindoia do Sul, Santa Catarina, in Brazil. Causes enzootic pneumonia in swine. This genus currently comprizes more than 120 obligate parasitic species found in the wide spectrum of hosts, including humans, animals, insects and plants. The primary habitats of human and animal mycoplasmas are mucouse membranes of the respiratory and urogenital tracts, eyes, mammary glands and the joints. Infection that proceeds through attachment of the bacteria to the host cell via specialized surface proteins, adhesins, and subsequent invation, results in prolonged intracellular persistence that may cause lethality. Once detected in association with their eukaryotic host tissue, most of mycoplasmas can be cultivated in the absence of a host if their extremely fastidious growth requirements are met.