Pre_GI: SWBIT SVG BLASTP

Query: NC_009953:691686 Salinispora arenicola CNS-205 chromosome, complete genome

Lineage: Salinispora arenicola; Salinispora; Micromonosporaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Found in marine sediment, this organism produces cancer-fighting compounds. Salinispora strains are commonly isolated from tropical marine sediment. Members of this genus produce branched hyphae and require media which contain seawater or sodium. A survey of the cultured species identified over 90 isolates which produce compounds that inhibited cancer cells. These organisms may be a new source of bioactive chemicals for use in disease and cancer treatments. Salinispora arenicola produces the bioactive compounds staurosporine and rifamycin which may be useful in the treatment of cancer.

Subject: NC_014623:1633889 Stigmatella aurantiaca DW4/3-1 chromosome, complete genome

Lineage: Stigmatella aurantiaca; Stigmatella; Cystobacteraceae; Myxococcales; Proteobacteria; Bacteria

General Information: Social gliding soil bacterium. Stigmatella aurantica, commonly isolated from rotting wood and bark, is a member of a group of organisms called myxobacteria. These organisms have a complex development and differentiation life cycle. When cell density increases, the organism switches to "social motility" where aggregates of cells can gather together into masses termed fruiting bodies that may consist of up to 100,000 cells. Stigmatella aurantica produces a number of compounds, such as aurafuron A and stigmatellin, which may be important as anti-cancer agents.