Pre_GI: SWBIT SVG BLASTP

Query: NC_009953:3852436 Salinispora arenicola CNS-205 chromosome, complete genome

Lineage: Salinispora arenicola; Salinispora; Micromonosporaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Found in marine sediment, this organism produces cancer-fighting compounds. Salinispora strains are commonly isolated from tropical marine sediment. Members of this genus produce branched hyphae and require media which contain seawater or sodium. A survey of the cultured species identified over 90 isolates which produce compounds that inhibited cancer cells. These organisms may be a new source of bioactive chemicals for use in disease and cancer treatments. Salinispora arenicola produces the bioactive compounds staurosporine and rifamycin which may be useful in the treatment of cancer.

Subject: NC_010682:288415 Ralstonia pickettii 12J chromosome 1, complete sequence

Lineage: Ralstonia pickettii; Ralstonia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria

General Information: Ralstonia pickettii 12J was isolated from copper-contaminated sediment from a lake in Michigan, USA. In addition to being highly resistant to copper, strain 12J is also resistant to zinc and cadmium. Ralstonia pickettii can be isolated from a wide range of environmental and clinical samples. This species is a nocosomial pathogen. It is associated with infections caused by contaminated solutions, such as distilled water and intravenous solutions. Ralstonia pickettii strains resistant to heavy metals have also been isolated from heavy metal contaminated environments.