Pre_GI: SWBIT SVG BLASTP

Query: NC_009953:2808288 Salinispora arenicola CNS-205 chromosome, complete genome

Lineage: Salinispora arenicola; Salinispora; Micromonosporaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Found in marine sediment, this organism produces cancer-fighting compounds. Salinispora strains are commonly isolated from tropical marine sediment. Members of this genus produce branched hyphae and require media which contain seawater or sodium. A survey of the cultured species identified over 90 isolates which produce compounds that inhibited cancer cells. These organisms may be a new source of bioactive chemicals for use in disease and cancer treatments. Salinispora arenicola produces the bioactive compounds staurosporine and rifamycin which may be useful in the treatment of cancer.

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Subject: NC_015434:3581001 Verrucosispora maris AB-18-032 chromosome, complete genome

Lineage: Verrucosispora maris; Verrucosispora; Micromonosporaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Verrucosispora sp. AB-18-032 is a filamentous bacterium belonging in the Micromonosporaceae family of the Actinobacteria. It produces abyssomicin (inhibitor of para-aminobenzoic acid biosynthesis which is an precursor of folic acid) and proximicin (furan-containing peptide with weak antibiotic effect and strong antitumor properties).