Query: NC_009953:2302337 Salinispora arenicola CNS-205 chromosome, complete genome
Lineage: Salinispora arenicola; Salinispora; Micromonosporaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Found in marine sediment, this organism produces cancer-fighting compounds. Salinispora strains are commonly isolated from tropical marine sediment. Members of this genus produce branched hyphae and require media which contain seawater or sodium. A survey of the cultured species identified over 90 isolates which produce compounds that inhibited cancer cells. These organisms may be a new source of bioactive chemicals for use in disease and cancer treatments. Salinispora arenicola produces the bioactive compounds staurosporine and rifamycin which may be useful in the treatment of cancer.
Subject: NC_006348:2372945 Burkholderia mallei ATCC 23344 chromosome 1, complete sequence
Lineage: Burkholderia mallei; Burkholderia; Burkholderiaceae; Burkholderiales; Proteobacteria; Bacteria
General Information: This type strain came from a Chinese patient in Burma who had glanders in 1944. Causes glanders in horses. This organism is rarely associated with human infection, and is more commonly seen in domesticated animals such as horses, donkeys, and mules where it causes glanders, a disease first described by Aristotle. The pathogen is host-adapted and is not found in the environment outside of its host. Rapid-onset pneumonia, bacteremia (spread of the organism through the blood), pustules, and death are common outcomes during infection. No vaccine exists for this potentially dangerous organism.