Query: NC_009921:5331565 Frankia sp. EAN1pec, complete genome
Lineage: Frankia; Frankia; Frankiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated at the Kettering Research Laboratory in Ohio, USA by M. Lalonde in 1978. It is resistant to lincomycin, kasugamycin, novobiocin, and, like many actinomycetes, to nalidixic acid. This strain is also resistant to elevated levels of lead, chromate, and arsenate.
Subject: NC_009142:5519208 Saccharopolyspora erythraea NRRL 2338, complete genome
Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.