Pre_GI: SWBIT SVG BLASTP

Query: NC_009900:1220082 Rickettsia massiliae MTU5, complete genome

Lineage: Rickettsia massiliae; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Rickettsia massiliae MTU5 was isolated from the tick Rhipicephalus turanicus collected from horses in Le Sambuc, Bouches-du Rhone, France. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia massiliae is a member of the spotted fever group of the Rickettsiales and has been isolated from ticks in Europe and Africa. Rickettsia massiliae does not appear to cause disease in humans.

Subject: NC_006832:627057 Ehrlichia ruminantium str. Welgevonden, complete genome

Lineage: Ehrlichia ruminantium; Ehrlichia; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This strain was obtained from an infected tick and maintained by serial infection in mice. Obligate intracellular bacterium and causative agent of heartwater. This organism causes heartwater, a disease with a high mortality rate that affects both wild and domesticated ruminants in sub-Saharan Africa and parts of the Caribbean. The name heartwater refers to the hydropericardium (excessive fluid in the sac surrounding the heart) commonly found associated with infection. This organism is found in membrane-bound vacuoles in endothelial cells and neutrophils and is an obligate intracellular parasite.