Query: NC_009881:283500 Rickettsia akari str. Hartford, complete genome Lineage: Rickettsia akari; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria General Information: This strain was isolated from mites in Hartford. Causative agent of Rickettsialpox. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia akari causes a mild disease, Rickettsialpox, which is an acute fever-inducing illness transmitted by a hematophagous mite that infects the common house mouse and bites humans. Infection by this organism may be confused with anthrax due to the black eschar. This bacterium is a member of the spotted fever group of Rickettsiales and is endemic to New York, USA, but is also found in other cities in the USA, Russia, South Korea, and South Africa.
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General Information: An endosymbiont of free-living amoebae (Acanthamoeba sp. endosymbiont UWE25) and implicated as a potential human pathogen this strain is an environmental isolate. Amoeba endosymbiont. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Candidatus Protochlamydia amoebophila, originally Parachlamydia is an endosymbiont of free-living amoebae (Acanthamoeba). This organism is an obligate intracellular endosymbiont and lives in small inclusions dispersed throughout the host cell.