Pre_GI: SWBIT SVG BLASTP

Query: NC_009785:387910 Streptococcus gordonii str. Challis substr. CH1, complete genome

Lineage: Streptococcus gordonii; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Normal human oral flora. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus gordonii is a commensal member of the human oral flora. It initiates the formation of biofilms on tooth surfaces known as dental plaque, which is strongly associated with the development of dental cavities (caries) and gum disease. It is a frequent causative agent of bacterial endocarditis (inflammation of the membrane lining the heart) which often occurs as a result of oral trauma, allowing S. gordonii to invade the bloodstream and colonize the heart.

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BLASTP Alignment.txt

Subject: NC_020995:3252500 Enterococcus casseliflavus EC20, complete genome

Lineage: Enterococcus casseliflavus; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium and faecalis. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains.