Pre_GI: SWBIT SVG BLASTP

Query: NC_009785:2124883 Streptococcus gordonii str. Challis substr. CH1, complete genome

Lineage: Streptococcus gordonii; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Normal human oral flora. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. Streptococcus gordonii is a commensal member of the human oral flora. It initiates the formation of biofilms on tooth surfaces known as dental plaque, which is strongly associated with the development of dental cavities (caries) and gum disease. It is a frequent causative agent of bacterial endocarditis (inflammation of the membrane lining the heart) which often occurs as a result of oral trauma, allowing S. gordonii to invade the bloodstream and colonize the heart.

Subject: NC_012470:258287 Streptococcus equi subsp. zooepidemicus, complete genome

Lineage: Streptococcus equi; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This bacterium is part of the normal bacterial flora in horses, however, it has also been isolated from a number of other mammals including humans. S. equi subsp. zooepidemicus is the cause of Inflammatory Airway Disease (IAD) in horses. This organism is also an opportunistic pathogen which can cause infections in the upper respiratory tract, uterus, umbilicus and in open wounds. Pathogenic in horses, goats and sheep. Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes.